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Prediction of novel target genes and pathways involved in irinotecan-resistant colorectal cancer
BACKGROUND: Acquired drug resistance to the chemotherapeutic drug irinotecan (the active metabolite of which is SN-38) is one of the significant obstacles in the treatment of advanced colorectal cancer (CRC). The molecular mechanism or targets mediating irinotecan resistance are still unclear. It is...
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| Pubblicato in: | PLoS One |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Public Library of Science
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5531462/ https://ncbi.nlm.nih.gov/pubmed/28749961 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0180616 |
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