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Expression of GITR Enhances Multiple Myeloma Cell Sensitivity to Bortezomib

Recently tumor necrosis factor receptor super family member 18 (TNFRSF18, also called GITR) has been identified as a novel tumor suppressor gene in Multiple Myeloma (MM), undergoing aberrant DNA methylation-mediated gene expression silencing. Furthermore, the expression of GITR blocks canonical NF-κ...

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Foilsithe in:PLoS One
Main Authors: Zhao, Yinghao, Zhang, Kun, Li, Guangquan, Zhang, Xingyi, Shi, Donglei
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2015
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4431824/
https://ncbi.nlm.nih.gov/pubmed/25973846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0127334
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