Formononetin Regulates Multiple Oncogenic Signaling Cascades and Enhances Sensitivity to Bortezomib in a Multiple Myeloma Mouse Model

Here, we determined the anti-neoplastic actions of formononetin (FT) against multiple myeloma (MM) and elucidated its possible mode of action. It was observed that FT enhanced the apoptosis caused by bortezomib (Bor) and mitigated proliferation in MM cells, and these events are regulated by nuclear...

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Библиографические подробности
Опубликовано в: :Biomolecules
Главные авторы: Kim, Chulwon, Lee, Jong Hyun, Ko, Jeong-Hyeon, Chinnathambi, Arunachalam, Alharbi, Sulaiman Ali, Shair, Omar H.M., Sethi, Gautam, Ahn, Kwang Seok
Формат: Artigo
Язык:Inglês
Опубликовано: MDPI 2019
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6681380/
https://ncbi.nlm.nih.gov/pubmed/31284669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom9070262
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