Formononetin Regulates Multiple Oncogenic Signaling Cascades and Enhances Sensitivity to Bortezomib in a Multiple Myeloma Mouse Model

Here, we determined the anti-neoplastic actions of formononetin (FT) against multiple myeloma (MM) and elucidated its possible mode of action. It was observed that FT enhanced the apoptosis caused by bortezomib (Bor) and mitigated proliferation in MM cells, and these events are regulated by nuclear...

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Publicat a:Biomolecules
Autors principals: Kim, Chulwon, Lee, Jong Hyun, Ko, Jeong-Hyeon, Chinnathambi, Arunachalam, Alharbi, Sulaiman Ali, Shair, Omar H.M., Sethi, Gautam, Ahn, Kwang Seok
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6681380/
https://ncbi.nlm.nih.gov/pubmed/31284669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom9070262
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