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Trichostatin A specifically improves the aberrant expression of transcription factor genes in embryos produced by somatic cell nuclear transfer

Although mammalian cloning by somatic cell nuclear transfer (SCNT) has been established in various species, the low developmental efficiency has hampered its practical applications. Treatment of SCNT-derived embryos with histone deacetylase (HDAC) inhibitors can improve their development, but the un...

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Bibliografische gegevens
Gepubliceerd in:Sci Rep
Hoofdauteurs: Inoue, Kimiko, Oikawa, Mami, Kamimura, Satoshi, Ogonuki, Narumi, Nakamura, Toshinobu, Nakano, Toru, Abe, Kuniya, Ogura, Atsuo
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2015
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4431350/
https://ncbi.nlm.nih.gov/pubmed/25974394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep10127
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