RNAi-mediated Knockdown of Xist Does Not Rescue the Impaired Development of Female Cloned Mouse Embryos

In mice, one of the major epigenetic errors associated with somatic cell nuclear transfer (SCNT) is ectopic expression of Xist during the preimplantation period in both sexes. We found that this aberrant Xist expression could be impeded by deletion of Xist from the putative active X chromosome in do...

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Detalhes bibliográficos
Main Authors: OIKAWA, Mami, MATOBA, Shogo, INOUE, Kimiko, KAMIMURA, Satoshi, HIROSE, Michiko, OGONUKI, Narumi, SHIURA, Hirosuke, SUGIMOTO, Michihiko, ABE, Kuniya, ISHINO, Fumitoshi, OGURA, Atsuo
Formato: Artigo
Idioma:Inglês
Publicado em: The Society for Reproduction and Development 2013
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3934135/
https://ncbi.nlm.nih.gov/pubmed/23363561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1262/jrd.2012-195
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