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Tuning the excitability of midbrain dopamine neurons by modulating the Ca(2+) sensitivity of SK channels

Small conductance Ca(2+) -activated K(+) (SK) channels play a prominent role in modulating the spontaneous activity of dopamine (DA) neurons as well as their response to synaptically-released glutamate. SK channel gating is dependent on Ca(2+) binding to constitutively bound calmodulin, which itself...

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Detalhes bibliográficos
Publicado no:Eur J Neurosci
Main Authors: Ji, Huifang, Hougaard, Charlotte, Herrik, Kjartan Frisch, Strøbæk, Dorte, Christophersen, Palle, Shepard, Paul D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4430859/
https://ncbi.nlm.nih.gov/pubmed/19473240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1460-9568.2009.06735.x
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