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Calcium-activated SK channels control firing regularity by modulating sodium channel availability in midbrain dopamine neurons

Dopamine neurons in the substantia nigra pars compacta and ventral tegmental area regulate behaviours such as reward-related learning, and motor control. Dysfunction of these neurons is implicated in Schizophrenia, addiction to drugs, and Parkinson’s disease. While some dopamine neurons fire single...

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Vydáno v:Sci Rep
Hlavní autoři: Iyer, Rajeshwari, Ungless, Mark A., Faisal, Aldo A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5507868/
https://ncbi.nlm.nih.gov/pubmed/28701749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-05578-5
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