Reprogramming Mouse Cells With a Pancreatic Duct Phenotype to Insulin-Producing β-Like Cells

Reprogramming technology has opened the possibility of converting one cell type into another by forced expression of transgenes. Transduction of adenoviral vectors encoding 3 pancreatic transcription factors, Pdx1, Ngn3, and MafA, into mouse pancreas results in direct reprogramming of exocrine cells...

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Опубликовано в: :Endocrinology
Главные авторы: Yamada, Takatsugu, Cavelti-Weder, Claudia, Caballero, Francisco, Lysy, Philippe A., Guo, Lili, Sharma, Arun, Li, Weida, Zhou, Qiao, Bonner-Weir, Susan, Weir, Gordon C.
Формат: Artigo
Язык:Inglês
Опубликовано: Endocrine Society 2015
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Original Research
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4430605/
https://ncbi.nlm.nih.gov/pubmed/25836667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2014-1987
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