Hyperglycaemia attenuates in vivo reprogramming of pancreatic exocrine cells to beta cells in mice

AIMS/HYPOTHESIS: Reprogramming of pancreatic exocrine to insulin-producing cells by viral delivery of the genes encoding transcription factors neurogenin-3 (Ngn3), pancreas/duodenum homeobox protein 1 (Pdx1) and MafA is an efficient method for reversing diabetes in murine models. The variables that...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Diabetologia
Hlavní autoři: Cavelti-Weder, Claudia, Li, Weida, Zumsteg, Adrian, Stemann-Andersen, Marianne, Zhang, Yuemei, Yamada, Takatsugu, Wang, Max, Lu, Jiaqi, Jermendy, Agnes, Bee, Yong Mong, Bonner-Weir, Susan, Weir, Gordon C., Zhou, Qiao
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4744133/
https://ncbi.nlm.nih.gov/pubmed/26693711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-015-3838-7
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky