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Hyperglycaemia attenuates in vivo reprogramming of pancreatic exocrine cells to beta cells in mice
AIMS/HYPOTHESIS: Reprogramming of pancreatic exocrine to insulin-producing cells by viral delivery of the genes encoding transcription factors neurogenin-3 (Ngn3), pancreas/duodenum homeobox protein 1 (Pdx1) and MafA is an efficient method for reversing diabetes in murine models. The variables that...
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| 出版年: | Diabetologia |
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| 主要な著者: | , , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4744133/ https://ncbi.nlm.nih.gov/pubmed/26693711 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-015-3838-7 |
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