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Pharmacokinetics of intravenous telavancin in healthy subjects with varying degrees of renal impairment

PURPOSE: We evaluated the effect of renal impairment (RI) on the pharmacokinetics of telavancin and hydroxypropylbetadex (excipient in the telavancin drug product). METHODS: Adults with normal, mild, moderate or severe RI or end-stage renal disease (ESRD) receiving haemodialysis were included in two...

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Pubblicato in:Eur J Clin Pharmacol
Autori principali: Worboys, Philip D., Wong, Shekman L., Barriere, Steven L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer Berlin Heidelberg 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4430595/
https://ncbi.nlm.nih.gov/pubmed/25939708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00228-015-1847-6
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