LC/MS analysis of cardiolipins in substantia nigra and plasma of rotenone-treated rats: implication for mitochondrial dysfunction in Parkinson's disease

Exposure to rotenone in vivo results in selective degeneration of dopaminergic neurons and development of neuropathological features of Parkinson's disease. As rotenone acts as an inhibitor of mitochondrial respiratory complex I, we employed oxidative lipidomics to assess oxidative metabolism o...

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Bibliografiska uppgifter
I publikationen:Free Radic Res
Huvudupphovsmän: Tyurina, Yulia Y., Polimova, Anastasia M., Maciel, Elisabete, Tyurin, Vladimir A., Kapralova, Valentina I., Winnica, Daniel E., Vikulina, Anna S., Domingues, Rosario M., McCoy, Jennifer, Sanders, Laurie H., Bayır, Hülya, Greenamyre, J. Timothy, Kagan, Valerian E.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2015
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4430340/
https://ncbi.nlm.nih.gov/pubmed/25740198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/10715762.2015.1005085
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