MicroRNAs Induce Epigenetic Reprogramming and Suppress Malignant Phenotypes of Human Colon Cancer Cells

Although cancer is a genetic disease, epigenetic alterations are involved in its initiation and progression. Previous studies have shown that reprogramming of colon cancer cells using Oct3/4, Sox2, Klf4, and cMyc reduces cancer malignancy. Therefore, cancer reprogramming may be a useful treatment fo...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Ogawa, Hisataka, Wu, Xin, Kawamoto, Koichi, Nishida, Naohiro, Konno, Masamitsu, Koseki, Jun, Matsui, Hidetoshi, Noguchi, Kozou, Gotoh, Noriko, Yamamoto, Tsuyoshi, Miyata, Kanjiro, Nishiyama, Nobuhiro, Nagano, Hiroaki, Yamamoto, Hirofumi, Obika, Satoshi, Kataoka, Kazunori, Doki, Yuichiro, Mori, Masaki, Ishii, Hideshi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4430240/
https://ncbi.nlm.nih.gov/pubmed/25970424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0127119
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