The Basal Transcription Complex Component TAF3 Transduces Changes in Nuclear Phosphoinositides into Transcriptional Output

Phosphoinositides (PI) are important signaling molecules in the nucleus that influence gene expression. However, if and how nuclear PI directly affects the transcriptional machinery is not known. We report that the lipid kinase PIP4K2B regulates nuclear PI5P and the expression of myogenic genes duri...

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Publicado no:Mol Cell
Main Authors: Stijf-Bultsma, Yvette, Sommer, Lilly, Tauber, Maria, Baalbaki, Mai, Giardoglou, Panagiota, Jones, David R., Gelato, Kathy A., van Pelt, Jason, Shah, Zahid, Rahnamoun, Homa, Toma, Clara, Anderson, Karen E., Hawkins, Philip, Lauberth, Shannon M., Haramis, Anna-Pavlina G., Hart, Daniel, Fischle, Wolfgang, Divecha, Nullin
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4429956/
https://ncbi.nlm.nih.gov/pubmed/25866244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2015.03.009
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