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The tumor suppressor LKB1 regulates starvation-induced autophagy under systemic metabolic stress

Autophagy is an evolutionarily conserved process that degrades cellular components to restore energy homeostasis under limited nutrient conditions. How this starvation-induced autophagy is regulated at the whole-body level is not fully understood. Here, we show that the tumor suppressor Lkb1, which...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Mans, Laurie A., Querol Cano, Laia, van Pelt, Jason, Giardoglou, Panagiota, Keune, Willem-Jan, Haramis, Anna-Pavlina G.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5544676/
https://ncbi.nlm.nih.gov/pubmed/28779098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-07116-9
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