Interferon-gamma inhibits scavenger receptor expression and foam cell formation in human monocyte-derived macrophages.
The scavenger receptor (ScR) mediates uptake of chemically modified low density lipoprotein (LDL) by human monocyte-derived macrophages. It is not down-regulated by high intracellular cholesterol levels, and exposure of macrophages to acetylated or oxidized LDL therefore leads to foam cell developme...
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| Publicado no: | J Clin Invest |
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| Principais autores: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
1992
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC442994/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1556191/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115718 |
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