Interferon-gamma inhibits scavenger receptor expression and foam cell formation in human monocyte-derived macrophages.

The scavenger receptor (ScR) mediates uptake of chemically modified low density lipoprotein (LDL) by human monocyte-derived macrophages. It is not down-regulated by high intracellular cholesterol levels, and exposure of macrophages to acetylated or oxidized LDL therefore leads to foam cell developme...

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Bibliografiske detaljer

Udgivet i:	J Clin Invest
Principais autores:	Geng, Y J, Hansson, G K
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Clinical Investigation 1992
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC442994/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1556191/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115718
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