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Biodistribution of Etanercept to Tissues and Sites of Inflammation in Arthritic Rats
Many monoclonal antibodies (mAbs) and other protein drugs have targets usually residing within tissues, making tissue concentrations of mAbs relevant to their pharmacologic effects. Therefore, knowledge of tissue distribution kinetics is important to better understand their pharmacokinetics and phar...
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| Vydáno v: | Drug Metab Dispos |
|---|---|
| Hlavní autoři: | , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
The American Society for Pharmacology and Experimental Therapeutics
2015
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4429683/ https://ncbi.nlm.nih.gov/pubmed/25834031 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.114.062901 |
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