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Modeling effects of dexamethasone on disease progression of bone mineral density in collagen-induced arthritic rats

A mechanism-based model was developed to characterize the crosstalk between proinflammatory cytokines, bone remodeling biomarkers, and bone mineral density (BMD) in collagen-induced arthritic (CIA) rats. Male Lewis rats were divided into five groups: healthy control, CIA control, CIA receiving singl...

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Detalhes bibliográficos
Publicado no:Pharmacol Res Perspect
Main Authors: Lon, Hoi-Kei, DuBois, Debra C, Earp, Justin C, Almon, Richard R, Jusko, William J
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Ltd 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4618640/
https://ncbi.nlm.nih.gov/pubmed/26516581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prp2.169
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