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Age-associated alterations in the micromechanical properties of chromosomes in the mammalian egg
PURPOSE: The incidence of aneuploidy in eggs from women of advanced reproductive age can exceed 60 %, making the mammalian egg a unique model system to study the mechanisms of chromosome segregation errors. METHODS: Here we applied a novel biophysical chromosome stretching approach to quantify mecha...
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| Publicado en: | J Assist Reprod Genet |
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| Autores principales: | , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Springer US
2015
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4429432/ https://ncbi.nlm.nih.gov/pubmed/25758987 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10815-015-0453-y |
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