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Dependence of the structure and mechanics of metaphase chromosomes on oxidized cysteines

We have found that reagents that reduce oxidized cysteines lead to destabilization of metaphase chromosome folding, suggesting that chemically linked cysteine residues may play a structural role in mitotic chromosome organization, in accord with classical studies (Dounce AL, Chanda SK, Townes PL (19...

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Detalhes bibliográficos
Publicado no:Chromosome Res
Main Authors: Eastland, Adrienne, Hornick, Jessica, Kawamura, Ryo, Nanavati, Dhaval, Marko, John F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4970972/
https://ncbi.nlm.nih.gov/pubmed/27145786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10577-016-9528-6
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