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Platelet-derived growth factor receptors on macrovascular endothelial cells mediate relaxation via nitric oxide in rat aorta.

The effects of platelet-derived growth factor (PDGF) were studied in isolated rings of rat aorta contracted submaximally to phenylephrine. The BB isoform of PDGF elicited relaxation in rings with endothelium and further contraction in rings without endothelium. Both the endothelium-dependent relaxat...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Principais autores: Cunningham, L D, Brecher, P, Cohen, R A
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1992
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC442933/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1311719/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115667
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