Platelet-derived growth factor receptors on macrovascular endothelial cells mediate relaxation via nitric oxide in rat aorta.

The effects of platelet-derived growth factor (PDGF) were studied in isolated rings of rat aorta contracted submaximally to phenylephrine. The BB isoform of PDGF elicited relaxation in rings with endothelium and further contraction in rings without endothelium. Both the endothelium-dependent relaxat...

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Publié dans:	J Clin Invest
Auteurs principaux:	Cunningham, L D, Brecher, P, Cohen, R A
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Clinical Investigation 1992
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC442933/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1311719/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115667
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