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Platelet-derived growth factor receptors on macrovascular endothelial cells mediate relaxation via nitric oxide in rat aorta.

The effects of platelet-derived growth factor (PDGF) were studied in isolated rings of rat aorta contracted submaximally to phenylephrine. The BB isoform of PDGF elicited relaxation in rings with endothelium and further contraction in rings without endothelium. Both the endothelium-dependent relaxat...

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Vydáno v:J Clin Invest
Hlavní autoři: Cunningham, L D, Brecher, P, Cohen, R A
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 1992
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC442933/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1311719/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115667
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