Donepezil for Irradiated Brain Tumor Survivors: A Phase III Randomized Placebo-Controlled Clinical Trial

PURPOSE: Neurotoxic effects of brain irradiation include cognitive impairment in 50% to 90% of patients. Prior studies have suggested that donepezil, a neurotransmitter modulator, may improve cognitive function. PATIENTS AND METHODS: A total of 198 adult brain tumor survivors ≥ 6 months after partia...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Clin Oncol
Egile Nagusiak: Rapp, Stephen R., Case, L. Doug, Peiffer, Ann, Naughton, Michelle M., Chan, Michael D., Stieber, Volker W., Moore, Dennis F., Falchuk, Steven C., Piephoff, James V., Edenfield, William J., Giguere, Jeffrey K., Loghin, Monica E., Shaw, Edward G.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society of Clinical Oncology 2015
Gaiak:
Original Reports
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4429174/
https://ncbi.nlm.nih.gov/pubmed/25897156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2014.58.4508
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