Donepezil for Irradiated Brain Tumor Survivors: A Phase III Randomized Placebo-Controlled Clinical Trial

PURPOSE: Neurotoxic effects of brain irradiation include cognitive impairment in 50% to 90% of patients. Prior studies have suggested that donepezil, a neurotransmitter modulator, may improve cognitive function. PATIENTS AND METHODS: A total of 198 adult brain tumor survivors ≥ 6 months after partia...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Clin Oncol
Prif Awduron: Rapp, Stephen R., Case, L. Doug, Peiffer, Ann, Naughton, Michelle M., Chan, Michael D., Stieber, Volker W., Moore, Dennis F., Falchuk, Steven C., Piephoff, James V., Edenfield, William J., Giguere, Jeffrey K., Loghin, Monica E., Shaw, Edward G.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society of Clinical Oncology 2015
Pynciau:
Original Reports
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4429174/
https://ncbi.nlm.nih.gov/pubmed/25897156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2014.58.4508
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