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Antitumor Effects of Fucoidan on Human Colon Cancer Cells via Activation of Akt Signaling

We identified a novel Akt signaling mechanism that mediates fucoidan-induced suppression of human colon cancer cell (HT29) proliferation and anticancer effects. Fucoidan treatment significantly inhibited growth, induced G1-phase-associated upregulation of p21WAF1 expression, and suppressed cyclin an...

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Detalhes bibliográficos
Publicado no:Biomol Ther (Seoul)
Main Authors: Han, Yong-seok, Lee, Jun Hee, Lee, Sang Hun
Formato: Artigo
Idioma:Inglês
Publicado em: The Korean Society of Applied Pharmacology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4428714/
https://ncbi.nlm.nih.gov/pubmed/25995820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4062/biomolther.2014.136
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