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Fucoidan Rescues p-Cresol-Induced Cellular Senescence in Mesenchymal Stem Cells via FAK-Akt-TWIST Axis

Mesenchymal stem cells (MSCs) are a source for cell-based therapy. Although MSCs have the potential for tissue regeneration, their therapeutic efficacy is restricted by the uremic toxin, p-cresol, in chronic kidney disease (CKD). To address this issue, we investigated the effect of fucoidan, a marin...

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Detalhes bibliográficos
Publicado no:Mar Drugs
Main Authors: Lee, Jun Hee, Yun, Chul Won, Hur, Jin, Lee, Sang Hun
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5923408/
https://ncbi.nlm.nih.gov/pubmed/29642406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md16040121
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