Sphingosine kinase 1 promotes the metastasis of colorectal cancer by inducing the epithelial-mesenchymal transition mediated by the FAK/AKT/MMPs axis

It was demonstrated that Sphingosine kinase 1 (SphK1) promotes tumor progression and confers the malignancy phenotype of colorectal cancer by activating the focal adhesion kinase (FAK) pathway. However, further clarification is required to determine if SphK1 promotes the metastasis of colorectal can...

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Bibliographische Detailangaben
Veröffentlicht in:Int J Oncol
Hauptverfasser: Liu, Shi-Quan, Xu, Chun-Yan, Wu, Wen-Hong, Fu, Zhen-Hua, He, Si-Wei, Qin, Meng-Bin, Huang, Jie-An
Format: Artigo
Sprache:Inglês
Veröffentlicht: D.A. Spandidos 2018
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6254930/
https://ncbi.nlm.nih.gov/pubmed/30365116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijo.2018.4607
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