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Melatonin Protects Human Renal Proximal Tubule Epithelial Cells Against High Glucose-Mediated Fibrosis via the Cellular Prion Protein-TGF-β-Smad Signaling Axis

Diabetes-mediated hyperglycemia is a major risk factor for renal fibrosis, resulting in the development of chronic kidney diseases. To address this issue, the effect of melatonin, which has an antioxidative potential, on renal fibrosis in human renal proximal tubule epithelial cells under high gluco...

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Detalhes bibliográficos
Publicado no:Int J Med Sci
Main Authors: Han, Yong-Seok, Yoon, Yeo Min, Go, Gyeongyun, Lee, Jun Hee, Lee, Sang Hun
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7294914/
https://ncbi.nlm.nih.gov/pubmed/32547319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijms.42603
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