"Mirror image" antagonists of thrombin-induced platelet activation based on thrombin receptor structure.
Platelet activation by thrombin plays a critical role in hemostasis and thrombosis. Based on structure-activity studies of a cloned platelet thrombin receptor, we designed two "mirror image" antagonists of thrombin and thrombin receptor function. First, "uncleavable" peptides mimicking the receptor...
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| 出版年: | J Clin Invest |
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| 主要な著者: | , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Clinical Investigation
1992
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC442871/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1310695/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115604 |
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