"Mirror image" antagonists of thrombin-induced platelet activation based on thrombin receptor structure.
Platelet activation by thrombin plays a critical role in hemostasis and thrombosis. Based on structure-activity studies of a cloned platelet thrombin receptor, we designed two "mirror image" antagonists of thrombin and thrombin receptor function. First, "uncleavable" peptides mimicking the receptor...
محفوظ في:
| الحاوية / القاعدة: | J Clin Invest |
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| المؤلفون الرئيسيون: | , , , , , , , |
| التنسيق: | Artigo |
| اللغة: | Inglês |
| منشور في: |
American Society for Clinical Investigation
1992
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| الموضوعات: | |
| الوصول للمادة أونلاين: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC442871/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1310695/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115604 |
| الوسوم: |
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