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Two Successive Reactions on a DNA Template: A Strategy for Improving Background and Specificity in Nucleic Acid Detection

We report a new strategy for template-mediated fluorogenic chemistry that results in enhanced performance for the fluorescence detection of nucleic acids. In this approach, two successive templated reactions are required to induce a fluorescence signal, rather than only one. These novel fluorescein-...

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Detaylı Bibliyografya
Yayımlandı:Chemistry
Asıl Yazarlar: Franzini, Raphael M., Kool, Eric T.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2011
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4428681/
https://ncbi.nlm.nih.gov/pubmed/21294182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.201002426
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