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Sandwich probes: two simultaneous reactions for templated nucleic acid detection
Fluorescence-quenched nucleic acid probes with reactive moieties at both the 5′ and 3′ ends are synthesized and tested for reaction with two adjacent nucleophile-containing DNAs. These probes improve signal to background over singly reactive probes and can discriminate single nucleotide polymorphism...
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| Publicat a: | Chem Commun (Camb) |
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| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2010
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5504956/ https://ncbi.nlm.nih.gov/pubmed/20927470 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c0cc01968b |
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