Calcium-responsive transactivator (CREST) protein shares a set of structural and functional traits with other proteins associated with amyotrophic lateral sclerosis

BACKGROUND: Mutations in calcium-responsive transactivator (CREST) encoding gene have been recently linked to ALS. Similar to several proteins implicated in ALS, CREST contains a prion-like domain and was reported to be a component of paraspeckles. RESULTS: We demonstrate that CREST is prone to aggr...

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Detalhes bibliográficos
Publicado no:Mol Neurodegener
Main Authors: Kukharsky, Michail S, Quintiero, Annamaria, Matsumoto, Taisei, Matsukawa, Koji, An, Haiyan, Hashimoto, Tadafumi, Iwatsubo, Takeshi, Buchman, Vladimir L, Shelkovnikova, Tatyana A
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4428507/
https://ncbi.nlm.nih.gov/pubmed/25888396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13024-015-0014-y
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