A Candida albicans CRISPR system permits genetic engineering of essential genes and gene families

Candida albicans is a pathogenic yeast that causes mucosal and systematic infections with high mortality. The absence of facile molecular genetics has been a major impediment to analysis of pathogenesis. The lack of meiosis coupled with the absence of plasmids makes genetic engineering cumbersome, e...

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Bibliographic Details
Published in:Sci Adv
Main Authors: Vyas, Valmik K., Barrasa, M. Inmaculada, Fink, Gerald R.
Format: Artigo
Language:Inglês
Published: American Association for the Advancement of Science 2015
Subjects:
Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4428347/
https://ncbi.nlm.nih.gov/pubmed/25977940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.1500248
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