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A Candida albicans CRISPR system permits genetic engineering of essential genes and gene families
Candida albicans is a pathogenic yeast that causes mucosal and systematic infections with high mortality. The absence of facile molecular genetics has been a major impediment to analysis of pathogenesis. The lack of meiosis coupled with the absence of plasmids makes genetic engineering cumbersome, e...
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| Опубликовано в: : | Sci Adv |
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| Главные авторы: | , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Association for the Advancement of Science
2015
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4428347/ https://ncbi.nlm.nih.gov/pubmed/25977940 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.1500248 |
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