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Expression and contributions of the Kir2.1 inward-rectifier K(+) channel to proliferation, migration and chemotaxis of microglia in unstimulated and anti-inflammatory states

When microglia respond to CNS damage, they can range from pro-inflammatory (classical, M1) to anti-inflammatory, alternative (M2) and acquired deactivation states. It is important to determine how microglial functions are affected by these activation states, and to identify molecules that regulate t...

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Publicado en:Front Cell Neurosci
Autores principales: Lam, Doris, Schlichter, Lyanne C.
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4428136/
https://ncbi.nlm.nih.gov/pubmed/26029054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2015.00185
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