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Responses of rat and mouse primary microglia to pro- and anti-inflammatory stimuli: molecular profiles, K(+) channels and migration

BACKGROUND: Acute CNS damage is commonly studied using rat and mouse models, but increasingly, molecular analysis is finding species differences that might affect the ability to translate findings to humans. Microglia can undergo complex molecular and functional changes, often studied by in vitro re...

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Detalhes bibliográficos
Publicado no:J Neuroinflammation
Main Authors: Lam, Doris, Lively, Starlee, Schlichter, Lyanne C.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5567442/
https://ncbi.nlm.nih.gov/pubmed/28830445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-017-0941-3
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