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Establishment of a patient-derived orthotopic osteosarcoma mouse model

BACKGROUND: Osteosarcoma (OS) is the most common pediatric primary malignant bone tumor. As the prognosis for patients following standard treatment did not improve for almost three decades, functional preclinical models that closely reflect important clinical cancer characteristics are urgently need...

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Detalhes bibliográficos
Publicado no:J Transl Med
Main Authors: Blattmann, Claudia, Thiemann, Markus, Stenzinger, Albrecht, Roth, Eva K, Dittmar, Anne, Witt, Hendrik, Lehner, Burkhard, Renker, Eva, Jugold, Manfred, Eichwald, Viktoria, Weichert, Wilko, Huber, Peter E, Kulozik, Andreas E
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4428092/
https://ncbi.nlm.nih.gov/pubmed/25926029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-015-0497-x
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