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Establishment of a patient-derived orthotopic osteosarcoma mouse model

BACKGROUND: Osteosarcoma (OS) is the most common pediatric primary malignant bone tumor. As the prognosis for patients following standard treatment did not improve for almost three decades, functional preclinical models that closely reflect important clinical cancer characteristics are urgently need...

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Bibliografische gegevens
Gepubliceerd in:J Transl Med
Hoofdauteurs: Blattmann, Claudia, Thiemann, Markus, Stenzinger, Albrecht, Roth, Eva K, Dittmar, Anne, Witt, Hendrik, Lehner, Burkhard, Renker, Eva, Jugold, Manfred, Eichwald, Viktoria, Weichert, Wilko, Huber, Peter E, Kulozik, Andreas E
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4428092/
https://ncbi.nlm.nih.gov/pubmed/25926029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-015-0497-x
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