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Establishment of a patient-derived orthotopic osteosarcoma mouse model

BACKGROUND: Osteosarcoma (OS) is the most common pediatric primary malignant bone tumor. As the prognosis for patients following standard treatment did not improve for almost three decades, functional preclinical models that closely reflect important clinical cancer characteristics are urgently need...

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Détails bibliographiques
Publié dans:J Transl Med
Auteurs principaux: Blattmann, Claudia, Thiemann, Markus, Stenzinger, Albrecht, Roth, Eva K, Dittmar, Anne, Witt, Hendrik, Lehner, Burkhard, Renker, Eva, Jugold, Manfred, Eichwald, Viktoria, Weichert, Wilko, Huber, Peter E, Kulozik, Andreas E
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4428092/
https://ncbi.nlm.nih.gov/pubmed/25926029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-015-0497-x
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