The alanine-serine-cysteine-1 (Asc-1) transporter controls glycine levels in the brain and is required for glycinergic inhibitory transmission

Asc-1 (SLC7A10) is an amino acid transporter whose deletion causes neurological abnormalities and early postnatal death in mice. Using metabolomics and behavioral and electrophysiological methods, we demonstrate that Asc-1 knockout mice display a marked decrease in glycine levels in the brain and sp...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:EMBO Rep
Hlavní autoři: Safory, Hazem, Neame, Samah, Shulman, Yoav, Zubedat, Salman, Radzishevsky, Inna, Rosenberg, Dina, Sason, Hagit, Engelender, Simone, Avital, Avi, Hülsmann, Swen, Schiller, Jackie, Wolosker, Herman
Médium: Artigo
Jazyk:Inglês
Vydáno: BlackWell Publishing Ltd 2015
Témata:
Scientific Reports
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4428048/
https://ncbi.nlm.nih.gov/pubmed/25755256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201439561
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky