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Nuclear lamins are not required for lamina-associated domain organization in mouse embryonic stem cells

In mammals, the nuclear lamina interacts with hundreds of large genomic regions, termed lamina-associated domains (LADs) that are generally in a transcriptionally repressed state. Lamins form the major structural component of the lamina and have been reported to bind DNA and chromatin. Here, we syst...

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Detalles Bibliográficos
Publicado en:EMBO Rep
Main Authors: Amendola, Mario, van Steensel, Bas
Formato: Artigo
Idioma:Inglês
Publicado: BlackWell Publishing Ltd 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4428043/
https://ncbi.nlm.nih.gov/pubmed/25784758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201439789
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