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Mouse B-Type Lamins Are Required for Proper Organogenesis But Not by Embryonic Stem Cells
B-type lamins, the major components of the nuclear lamina, are believed to be essential for cell proliferation and survival. We found that mouse embryonic stem cells (ESCs) do not need any lamins for self-renewal and pluripotency. Although genome-wide lamin-B binding profiles correlate with reduced...
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| 主要な著者: | , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2011
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3306219/ https://ncbi.nlm.nih.gov/pubmed/22116031 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1211222 |
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