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Lamina-associated domains: links with chromosome architecture, heterochromatin and gene repression
In metazoan cell nuclei, hundreds of large chromatin domains are in close contact with the nuclear lamina. Such lamina-associated domains (LADs) are thought to help organize chromosomes inside the nucleus and have been associated with gene repression. Here, we discuss the properties of LADs, the mol...
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| Опубликовано в: : | Cell |
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| Главные авторы: | , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2017
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5532494/ https://ncbi.nlm.nih.gov/pubmed/28525751 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2017.04.022 |
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