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Lamina-associated domains: links with chromosome architecture, heterochromatin and gene repression

In metazoan cell nuclei, hundreds of large chromatin domains are in close contact with the nuclear lamina. Such lamina-associated domains (LADs) are thought to help organize chromosomes inside the nucleus and have been associated with gene repression. Here, we discuss the properties of LADs, the mol...

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Detalhes bibliográficos
Publicado no:Cell
Main Authors: van Steensel, Bas, Belmont, Andrew S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5532494/
https://ncbi.nlm.nih.gov/pubmed/28525751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2017.04.022
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