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Lamina-associated domains: links with chromosome architecture, heterochromatin and gene repression
In metazoan cell nuclei, hundreds of large chromatin domains are in close contact with the nuclear lamina. Such lamina-associated domains (LADs) are thought to help organize chromosomes inside the nucleus and have been associated with gene repression. Here, we discuss the properties of LADs, the mol...
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| Publicado no: | Cell |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5532494/ https://ncbi.nlm.nih.gov/pubmed/28525751 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2017.04.022 |
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