Development of genetically engineered iNKT cells expressing TCRs specific for the M. tuberculosis 38-kDa antigen

INTRODUCTION: The invariant natural killer T (iNKT) cell has been shown to play a central role in early stages immune responses against Mycobacterium tuberculosis (Mtb) infection, which become nonresponsive (anergic) and fails to control the growth of Mtb in patients with active tuberculosis. Enhanc...

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Detalhes bibliográficos
Publicado no:J Transl Med
Main Authors: Jiang, Zhen-Min, Luo, Wei, Wen, Qian, Liu, Su-Dong, Hao, Pei-Pei, Zhou, Chao-Ying, Zhou, Ming-Qian, Ma, Li
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4428004/
https://ncbi.nlm.nih.gov/pubmed/25943357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-015-0502-4
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