Mutated BRAF Emerges as a Major Effector of Recurrence in a Murine Melanoma Model After Treatment With Immunomodulatory Agents

We used a VSV-cDNA library to treat recurrent melanoma, identifying immunogenic antigens, allowing us to target recurrences with immunotherapy or chemotherapy. Primary B16 melanoma tumors were induced to regress by frontline therapy. Mice with recurrent tumors were treated with VSV-cDNA immunotherap...

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Veröffentlicht in:Mol Ther
Hauptverfasser: Zaidi, Shane, Blanchard, Miran, Shim, Kevin, Ilett, Elizabeth, Rajani, Karishma, Parrish, Christopher, Boisgerault, Nicolas, Kottke, Tim, Thompson, Jill, Celis, Esteban, Pulido, Jose, Selby, Peter, Pandha, Hardev, Melcher, Alan, Harrington, Kevin, Vile, Richard
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2015
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4427869/
https://ncbi.nlm.nih.gov/pubmed/25544599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2014.253
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