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Loss of Bace1 in Mice Does Not Alter the Severity of Caerulein Induced Pancreatitis

CONTEXT: Beta-site alpha-amyloid protein cleaving enzyme1 (BACE1) plays a key role in the pathogenesis of Alzheimer’s disease. Additional to its moderate expression in the brain, high levels of BACE1 mRNA were found in the pancreas. Murine Bace1 has been immunohistochemicaly detected at the apical p...

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Detalhes bibliográficos
Publicado no:PLoS One
Principais autores: Heindl, Mario, Tuennemann, Jan, Sommerer, Ines, Mössner, Joachim, Hoffmeister, Albrecht
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4427297/
https://ncbi.nlm.nih.gov/pubmed/25961820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0125556
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