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A malarial cysteine proteinase is necessary for hemoglobin degradation by Plasmodium falciparum.

To obtain free amino acids for protein synthesis, trophozoite stage malaria parasites feed on the cytoplasm of host erythrocytes and degrade hemoglobin within an acid food vacuole. The food vacuole appears to be analogous to the secondary lysosomes of mammalian cells. To determine the enzymatic mech...

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Detalles Bibliográficos
Main Authors: Rosenthal, P J, McKerrow, J H, Aikawa, M, Nagasawa, H, Leech, J H
Formato: Artigo
Idioma:Inglês
Publicado: 1988
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC442723/
https://ncbi.nlm.nih.gov/pubmed/3053784
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