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Paradoxical fate and biological action of peroxynitrite on human platelets.

Peroxynitrite (ONOO-), which is formed from the reaction of nitric oxide (NO) and superoxide (O2-), has been suggested to be responsible for some of the cytotoxic effects of these molecules. When protonated, ONOO- gives rise to hydroxyl (OH.) and nitrogen dioxide (NO2) radicals, which are capable of...

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Detalhes bibliográficos
Main Authors: Moro, M A, Darley-Usmar, V M, Goodwin, D A, Read, N G, Zamora-Pino, R, Feelisch, M, Radomski, M W, Moncada, S
Formato: Artigo
Idioma:Inglês
Publicado em: 1994
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC44271/
https://ncbi.nlm.nih.gov/pubmed/7517561
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