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Kinetic and mechanistic considerations to assess the biological fate of peroxynitrite

BACKGROUND: Peroxynitrite, the product of the reaction between superoxide radicals and nitric oxide, is an elusive oxidant of short half-life and low steady-state concentration in biological systems; it promotes nitroxidative damage. SCOPE OF REVIEW: We will consider kinetic and mechanistic aspects...

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Detalhes bibliográficos
Main Authors: Carballal, Sebastián, Bartesaghi, Silvina, Radi, Rafael
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3858447/
https://ncbi.nlm.nih.gov/pubmed/23872352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagen.2013.07.005
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